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Synthese und antikonvulsive Eigenschaften einiger neuer Chinazolinon‐thiosemicarbazon‐ und 4‐Thiazolidon‐ Derivate
Author(s) -
ElFeky S. A. H.,
Abd ElSamii Z. K.
Publication year - 1991
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19913240613
Subject(s) - anticonvulsant , quinazolinone , chemistry , semicarbazone , biological activity , hypnotic , alkyl , stereochemistry , aryl , chemical synthesis , pharmacology , epilepsy , organic chemistry , biochemistry , medicine , in vitro , psychiatry
Diverse biological activities have been found in compounds having a quinazolinone ring system 1) . A large number of 4(3 H )‐quinazolinones, in particular those possessing 2‐alkyl‐3‐aryl 2) , 2,3‐dialkyl 3) , and 2‐alkyl‐3‐amino 4) substitution, have been evaluated for pharmacological activity. On the other hand, thiazolidone derivatives are reported to have anesthetic 5) , anticonvulsant 6) , and hypnotic 7) activity.