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N ‐[4‐(3 H ‐1,3,4‐Oxadiazolin‐2‐thion‐5‐yl)phenyl]‐ N ′‐substituierte Thioharnstoffe: Synthese und antibakterielle Aktivität
Author(s) -
Rollas Sevim,
Büyüktimkin Servet,
Çevikbas Adile
Publication year - 1991
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19913240312
Subject(s) - thiourea , antimicrobial , chemistry , fungicide , sulfur , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , biology , botany
Diverse pharmacological properties are associated with 3 H ‐1,3,4‐oxadiazoline‐2‐thione derivatives. These include anticonvulsant 1—4) and fungicidal 5) properties. On the other hand thiourea derivatives possess antiphytoviral 6) , virucidal 7) , growth inhibitory 8—10) , and herbicide 11) activities. All these data prompted us to combine these moieties into a single molecule. The compounds synthesized were tested for their antimicrobial activities against seven microorganisms.