Synthesis and Antimicrobiological Activity of  N ‐Aryl‐substituted 2‐Methyl‐3‐carbethoxy‐5‐pyrrolinone Derivatives | Zendy

Lovren Fina | Zendy; Gaon Igor D. | Zendy; Bobarevic Blanka | Zendy

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Synthesis and Antimicrobiological Activity of N ‐Aryl‐substituted 2‐Methyl‐3‐carbethoxy‐5‐pyrrolinone Derivatives

Author(s) -

Lovren Fina,

Gaon Igor D.,

Bobarevic Blanka

Publication year - 1990

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19903231104

Subject(s) - chemistry , antimicrobial , aryl , aniline , fungicide , biological activity , condensation , organic chemistry , chemical synthesis , medicinal chemistry , alkyl , in vitro , biochemistry , botany , physics , biology , thermodynamics

We describe the synthesis of N ‐aryl‐2‐methyl‐3‐carbethoxy‐5‐pyrrolinones benzylidene derivatives, their condensation with azomethines and substitution with aniline. The compounds have been tested for antimicrobial and fungicide activity: they have better fungicidal than bactericidal activity.

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