Premium
Synthesis and Antimicrobiological Activity of N ‐Aryl‐substituted 2‐Methyl‐3‐carbethoxy‐5‐pyrrolinone Derivatives
Author(s) -
Lovren Fina,
Gaon Igor D.,
Bobarevic Blanka
Publication year - 1990
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19903231104
Subject(s) - chemistry , antimicrobial , aryl , aniline , fungicide , biological activity , condensation , organic chemistry , chemical synthesis , medicinal chemistry , alkyl , in vitro , biochemistry , botany , physics , biology , thermodynamics
We describe the synthesis of N ‐aryl‐2‐methyl‐3‐carbethoxy‐5‐pyrrolinones benzylidene derivatives, their condensation with azomethines and substitution with aniline. The compounds have been tested for antimicrobial and fungicide activity: they have better fungicidal than bactericidal activity.