Endogenous Alkaloids in Man, VII 1 ): 1‐Trichloromethyl‐1,2,3,4‐tetrahydro‐β‐carboline ‐ A Potential Chloral‐Derived Indol Alkaloid in Man

The trichloromethyl tetrahydro‐β‐carboline 5 , an imaginable, chloral‐derived mammalian indol “alkaloid”, was prepared in high yields and was shown to be formed even under mild, physiological conditions, in aqueous medium. For its detection in low concentrations, a chromatographic procedure was elaborated. Furthermore, its potential metabolite 8 was synthesized for the first time.