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Synthesis and Pharmacological Studies of Some (1,4)‐Naphthoquinono[3,2‐c]‐1H‐pyrazoles,2‐Substituted Amino‐1,4‐naphthoquinones, and Related Compounds
Author(s) -
Tandon V. K.,
Vaish Meenu,
Khanna J. M.,
Anand Nitya
Publication year - 1990
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19903230702
Subject(s) - chemistry , stereochemistry , chemical synthesis , combinatorial chemistry , biochemistry , in vitro
Series of (1,4)‐Naphthoquinono(3,2‐c)‐1H‐pyrazoles and 2‐substituted amino‐1,4‐naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity ( C. neoformans, T. mentagraphytes, M. canis, A. niger , and C. albicans ).