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Racemic Modification of (R,S)‐3‐(4‐Phenyl‐1‐piperazinyl)‐1,2‐propandiol and Melting Point Diagram
Author(s) -
Pitrè Davide,
Stradi Riccardo
Publication year - 1990
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19903230107
Subject(s) - enantiomer , melting point , diagram , chemistry , stereochemistry , organic chemistry , mathematics , statistics
The results of D.S.C., I.R.‐ and X Ray‐Diffraction studies on (R,S)‐3‐(4‐phenyl‐1‐piperazinyl)‐1,2‐propandiol ( 1 ) and on its S(−)‐enantiomer ( 2 ) are consistent with the definition of “racemic compound” for ( 1 ). The melting point diagram has been plotted theoretically through D.S.C. data and then confirmed experimentally. In this way the calorimetric determination of enantiomeric purity has a precise reference.
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