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Synthesis and Ca‐Antagonist Activity of Some Benzhydryl Derivatives
Author(s) -
Corsano Stefano,
Strappaghetti Giovannella,
Domenico Elsa Di,
Brasili Livio,
Picchio Maria Teresa
Publication year - 1989
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19893221207
Subject(s) - cinnarizine , chemistry , antagonist , taenia coli , pharmacology , calcium , stereochemistry , organic chemistry , chromatography , biochemistry , receptor , medicine
The preparation of a series of benzhydryl derivatives is described. Their activities as Calcium‐antagonists were evaluated on the taenia coli of the guineapig. These new compunds show lower activities as Ca‐antagonists than Cinnarizine.