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The Effect of Aryl Substituents in Some Spiro[2‐oxo‐4, 6‐bis (aryl)hexahydropyrimidine‐5,5′‐barbituric acids]
Author(s) -
Mokrosz Jerzy L.,
Paluchowska Maria H.,
Szneler Edward,
Drozdz Barbara
Publication year - 1989
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19893220408
Subject(s) - chemistry , aryl , substituent , fragmentation (computing) , mass spectrum , barbituric acid , stereochemistry , nmr spectra database , medicinal chemistry , spectral line , organic chemistry , alkyl , physics , astronomy , computer science , operating system , ion
The substituent effects on the pK a1 values and 13C‐NMR spectra of the structurally hindered spirobarbiturates 1 – 7 are discussed. The electron impact mass spectra of these compounds are examined and their fragmentation patterns are proposed.