Premium
6‐Chloro‐1,2,4‐triazolo[4,3‐b]pyrido[2,3‐d]‐and [3,2‐d]pyridazines ‐ Synthesis and Structure Determination
Author(s) -
Hassan M. A.,
Fahmy A. F. M.
Publication year - 1988
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19883211223
Subject(s) - pyridazine , hydrazine (antidepressant) , hydrate , chemistry , formic acid , stereochemistry , medicinal chemistry , organic chemistry , chromatography
5,8‐Dichloropyrido[2,3‐d]pyridazine ( 2 ) gave with hydrazine hydrate in dioxane 5‐chloro‐8‐hydrazino‐ and 8‐chloro‐5‐hydrazinopyrido[2,3‐d]pyridazines 3 and 4 . When 3 and 4 were allowed to react with formic acid they gave a mixture of the 6‐chloro‐1,2,4‐triazolo[4,3‐b]pyrido[2,3‐d] ‐ and [3,2‐d]pyridazines ( 5 and 6 ).