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Activated Nitriles in Heterocyclic Synthesis: Novel Syntheses of Pyrano[2,3‐ b ]pyridines and Pyrano[2,3‐ d ]pyrimidines
Author(s) -
Elgemeie Galal E. H.,
ElKerim Abd,
Gohar M.,
Regaila Hassan A.,
Elfahham Hassan A.
Publication year - 1988
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19883210304
Subject(s) - acrylonitrile , chemistry , ethyl acetoacetate , pyrimidine , pyridine , nitrile , organic chemistry , stereochemistry , catalysis , polymer , copolymer
Reactions of β‐(2‐furanyl)‐ and β‐(2‐thienyl)‐acrylonitrile with ethyl acetoacetate are reported. They lead to new polyfunctional derivatives of pyrano[2,3‐ b ]pyridine and pyrano[2,3‐ d ]‐pyrimidine. The structures of these products and the mechanisms of their formation are reported.