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Determination of Optical Purity by Mass Spectrometry
Author(s) -
Lee DongUng,
Mayer Klaus K.,
Wiegrebe Wolfgang
Publication year - 1988
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19883210104
Subject(s) - isotope dilution , mass spectrometry , chemistry , deuterium , chromatography , analytical chemistry (journal) , ethyl chloroformate , isotope , dilution , physics , quantum mechanics , thermodynamics
MS‐Isotope Dilution Analysis (MS‐IDA) with deuterated 2 as standard was used to determine the optical purity of crystalline (+)‐ 2 , obtained from optically pure (+)‐ 1 with ethyl chloroformate.

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