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Darstellung von 6‐(Ethoxymethylenimino)‐1,2,4‐triazolo[3′,4′:5,1] [1,2,4]triazolo[4,3‐ a ]chinazolin‐7(6 H )‐one
Author(s) -
Liu KangChien,
Hu MingKuan
Publication year - 1987
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19873200817
Subject(s) - quinazolinone , chemistry , stereochemistry , combinatorial chemistry , medicinal chemistry
As a progressive continuation of our study in the condensed quinazolinone series 1, 2) , we recently described the synthesis and antihypertensive activity of some 4‐amino[1,2,4]triazolo[4,3‐a]quinazolin‐5(4H)‐one derivatives ( 1a‐c , R=H, OH, SH). Now, we wish to report the conversion of one of these derivatives, namely 4‐amino‐1‐mercapto‐[1,2,4]‐triazolo[4,3‐a]quinazolin‐5(4H)‐one (1c) into a more complicate condensed quinazolinone system.