Derivatives of 2‐Amino‐1,2,3,4‐tetrahydronaphthalene XI 1 ): trans ‐6,9‐Dimethoxy‐2,3,4a,5,10,10a‐hexahydro‐4 H ‐naphth[2,3‐ b ]1,4‐oxazines ‐ Tricyclic Analogs of trans ‐2‐Amino‐3‐hydroxy‐5,8‐dimethoxytetralins

Cyclization of chloroacetyl derivatives of the aminotetraloles 2 and 3 in alcoholic KOH yields 3‐oxonaphthalane‐morpholines. Their reduction with LiAlH 4 gave the naphthalane‐morpholines 5 . The pharmacological screening of 5a ′ showed central stimulative, peripheral adrenergic, and analgetic activities.