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Synthesis of New 3‐(Pyridin‐6‐yl)pyrazolo[1,5‐ a ]pyrimidines
Author(s) -
Ibrahim Nadia Sobhy,
Mohamed Mona Hassan,
Elnagdi Mohamed Hilmy
Publication year - 1987
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19873200603
Subject(s) - chemistry , ethyl cyanoacetate , stereochemistry , bicyclic molecule , medicinal chemistry , malononitrile , organic chemistry , catalysis
New 3‐(pyridin‐6‐yl)pyrazolo[1,5‐ a ]pyrimidines were synthesized from (pyridin‐6‐yl)malonodinitrile 5a , ethyl (pyridin‐6‐yl)cyanoacetate 5b and (pyridin‐6‐yl)benzoylacetonitrile 5c. Compounds 5a‐c were obtained from the 4,4,4‐trichlorobut‐2‐enenitriles 2 and 1‐phenylethylidene)malonodinitrile (1) .
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