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Syntheses and Biological Activities of 2‐(Adamantylmethyl)benzimidazoles and ‐imidazolines
Author(s) -
Kuźmierkiewicz Wojciech,
Sa̧czewski Franciszek,
Foks Henryk,
Kaliszan Roman,
Damasiewicz Barbara,
Nasal Antoni,
Radwańska Aleksandra
Publication year - 1986
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19863190910
Subject(s) - benzimidazole , chemistry , substituent , imidazoline receptor , biological activity , combinatorial chemistry , chemical synthesis , organic chemistry , stereochemistry , pharmacology , biochemistry , in vitro , biology
Derivatives of benzimidazole and imidazoline with a 2‐(adamantylmethyl) substituent were obtained by direct fusion of adamantaneacetic acids and suitable diamines. Some of the compounds synthesised show significant circulatory and tuberculostatic activity.