Studies on Histaminergic Compounds, III. Synthesis and Histamine H 2 ‐Activity of a Series of Corresponding Histamine and Dimaprit Analogues | Zendy

Sterk G. J. | Zendy; Van Goot H. Der | Zendy; Timmerman H. | Zendy

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Studies on Histaminergic Compounds, III. Synthesis and Histamine H 2 ‐Activity of a Series of Corresponding Histamine and Dimaprit Analogues

Author(s) -

Sterk G. J.,

Van Goot H. Der,

Timmerman H.

Publication year - 1986

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19863190710

Subject(s) - dimaprit , histaminergic , histamine , chemistry , histamine h2 receptor , stereochemistry , series (stratigraphy) , histamine receptor , histamine h3 receptor , receptor , pharmacology , biochemistry , antagonist , biology , paleontology

Structure‐activity relationships of a series of histamine analogues were found to be identical, except for one minor discrepancy, to those of a series of corresponding dimaprit analogues. It was concluded that histamine and dimaprit most probably interact with the same binding sites of the histamine H 2 ‐receptor.

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