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Synthesis and Antimycotic Activity of some 3‐(1‐Imidazolylmethyl)indoles
Author(s) -
Gatti Rita,
Cavrini Vanni,
Roveri Paola,
Luglio Glulia
Publication year - 1985
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19853180210
Subject(s) - chemistry , stereochemistry , traditional medicine , pharmacology , organic chemistry , medicine
Abstract The title compounds were synthesized and tested for their in vitro antimycotic activity. 1‐Ethyl‐3‐{[2,4‐dichloro‐α‐(1‐imidazolyl)]phenethyl}indole ( 5 ) exhibited appreciable activity against Cr. neoformans (MIC = 12,5μg/ml).