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Indole Derivatives Related to Lonidamine
Author(s) -
Andreani Aldo,
Rambaldi Mirella,
Bonazzi Daniela,
Andreani Franco,
Bossa Rosaria,
Galatulas Iraklis
Publication year - 1984
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19843171007
Subject(s) - substituent , indole test , chemistry , derivative (finance) , stereochemistry , chemical synthesis , combinatorial chemistry , in vitro , biochemistry , financial economics , economics
The synthesis and the antitumor activities of 1‐benzylindole‐3‐carboxylic acids are reported. Compound 16b , which bears at position 1 the same substituent as Lonidamine (1) , proved to be the most active derivative.
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