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Syntheses and Biological Activities of 3‐[4‐(Alkoxycarbonyl)phenyl]sydnones and their Derivatives
Author(s) -
Pattanashetti Panchaling P.,
Tikare Ravindra K.,
Dambal Devaraddi B.,
Badami Bharati V.,
Puranik Gurubasav S.
Publication year - 1984
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19843170112
Subject(s) - sydnone , chemistry , antimicrobial , hydrazide , fragmentation (computing) , organic chemistry , combinatorial chemistry , medicinal chemistry , ring (chemistry) , computer science , operating system
Four new 3‐[4‐(alkoxycarbonyl)phenyl]sydnones have been synthesised. The hydrazide 4 is condensed with various aromatic aldehydes to obtain the corresponding Schiff bases. Antimicrobial activities of the sydnones and some Schiff bases are reported. Mass spectral fragmentation of 3[4‐(ethoxycarbonyl)phenyl]sydnone is discussed.