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Preparation of 1‐(Aroylalkyl)‐1 H ‐imidazole and ‐Benzimidazole Derivatives of Pharmaceutical Interest. A New Synthetic Procedure
Author(s) -
Pellicciari Roberto,
Curini Massimo,
Spagnoli Nicoletta
Publication year - 1984
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19843170108
Subject(s) - benzimidazole , imidazole , chemistry , diazo , combinatorial chemistry , aryl , organic chemistry , stereochemistry , alkyl
Abstract A simple and improved procedure for the preparation of the title compounds is described. It is based on the copper‐bronze catalyzed decomposition of aryl diazo ketones in the presence of imidazolic substrates.