Derivatives of 2‐Amino‐1,2,3,4‐Tetrahydronaphthalene, VIII. 1 ) Isomerization of  trans ‐2‐Acetamido‐3‐hydroxy‐5,8‐dimethoxy‐1,2,3,4‐tetrahydronaphthalene and Hydrolysis of 5,8‐Dimethoxy‐2‐methyl‐3 a ,4,9,9 a ‐tetrahydronaphth[2,3‐ d ]oxazoline Hydrochloride | Zendy

Christova Kristina | Zendy; Dantschev Damjan | Zendy

Premium

Derivatives of 2‐Amino‐1,2,3,4‐Tetrahydronaphthalene, VIII. 1 ) Isomerization of trans ‐2‐Acetamido‐3‐hydroxy‐5,8‐dimethoxy‐1,2,3,4‐tetrahydronaphthalene and Hydrolysis of 5,8‐Dimethoxy‐2‐methyl‐3 a ,4,9,9 a ‐tetrahydronaphth[2,3‐ d ]oxazoline Hydrochloride

Author(s) -

Christova Kristina,

Dantschev Damjan

Publication year - 1983

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19833160905

Subject(s) - isomerization , chemistry , hydrolysis , hydrochloride , oxazoline , medicinal chemistry , stereochemistry , chloride , organic chemistry , catalysis

The isomerization of trans ‐2‐acetamido‐3‐hydroxy‐5,8‐dimethoxytetraline (1) under the action of hydrogen chloride was investigated. Hydrolysis of 5,8‐dimethoxy‐2‐methyl‐3 a ,4,9,9 a ‐tetrahydronaphth[2,3‐ d ]oxazoline hydrochloride (2) leads to cis ‐2‐amino‐3‐hydroxy‐5,8‐dimethoxytetraline (3) .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research