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Reactions with Heterocyclic Amidines, XI. Syntheses of New 2‐Aminopyrazolo[1,5—a]pyrimidines and 2‐Amino[1,5‐c]‐as‐triazines
Author(s) -
Kandeel Ezzat M.,
Baghos Victorin B.,
Mohareb Ivon S.,
Elnagdi Mohamed H.
Publication year - 1983
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19833160813
Subject(s) - chemistry , bifunctional , reagent , pyrazole , amidine , condensation reaction , condensation , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , physics , thermodynamics
Several new aminopyrazolo[1,5— a ]pyrimidines were synthesised by condensation of 3,5‐diamino‐4‐(ethoxycarbonyl)pyrazole (1) with β‐bifunctional reagents. The azo analogues of pyrazolo[1,5— a ]pyrimidines, i. e. pyrazolo[1,4‐ c ]‐ as ‐triazines, were synthesised by coupling of diazotized 1 with agents containing active hydrogen.