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Reactions with Activated Nitriles: Some new Approaches to the Synthesis of Pyridine Derivatives
Author(s) -
Daboun Hamed A.,
Abdou Sadek E.,
Khader Mahmoud M.
Publication year - 1983
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19833160616
Subject(s) - pyridine , chemistry , combinatorial chemistry , chemical synthesis , organic chemistry , biochemistry , in vitro
Several new pyridine derivatives were synthesised by the reaction of 2‐amino‐1,1,3‐tricyanopropene (2) with acetylacetone and salicyl aldehyde and treatment of the products with active methylene reagents and hydrazines. The structures of the isolated products were established by analytical, IR and 1 H‐NMR data.