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Cyclovinylogues of Procainamide
Author(s) -
Valenti Piero,
Mazzotti Maurizia,
Rampa Angela,
Magistretti Maria J.
Publication year - 1982
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19823151205
Subject(s) - procainamide , chemistry , methylene , benzene , dissociation (chemistry) , stereochemistry , medicinal chemistry , anesthesia , organic chemistry , medicine
Three isomeric cyclovinylogues of procainamide, in which a benzene ring is interposed between the methylene groups of the basic chain, are described. Appreciable dissociation has been achieved between local anesthetic and antiarrhythmic activities.