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Synthesis of Some Metabolites of Promethazine
Author(s) -
Clement Bernd,
Beckett Arnold H.
Publication year - 1981
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19813140812
Subject(s) - promethazine , chemistry , metabolite , oxime , stereochemistry , chemical synthesis , pharmacology , organic chemistry , biochemistry , biology , in vitro
The synthesis of the N ‐methylnitrone 11 , N ‐monoalkylhydroxylamine 9 , N,N ‐dialkylhydroxylamine 10 , Oxime 8 and other potential metabolites of promethazine (1) and of its N ‐dealkyl derivatives 2,3 are described.
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