Mass Spectral and Antimicrobial Studies of the Benzofuran Analog of Chloramphenicol | Zendy

Bevinakatti Hanamanthsa S. | Zendy; Badiger Virupax V. | Zendy

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Mass Spectral and Antimicrobial Studies of the Benzofuran Analog of Chloramphenicol

Author(s) -

Bevinakatti Hanamanthsa S.,

Badiger Virupax V.

Publication year - 1981

Publication title -

archiv der pharmazie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.468

H-Index - 61

eISSN - 1521-4184

pISSN - 0365-6233

DOI - 10.1002/ardp.19813140212

Subject(s) - chloramphenicol , benzofuran , chemistry , antimicrobial , diol , propane , antifungal , combinatorial chemistry , in vitro , ion , stereochemistry , antibiotics , organic chemistry , biochemistry , microbiology and biotechnology , biology

1‐(2‐Benzofuranyl)‐2‐(dichloroacetamido)propane‐1,3‐diol breaks down in a well‐defined manner upon electron impact. The principal ions formed are characterised and the most plausible mechanism of their formation is discussed. The results of in vitro antibacterial and antifungal screening of the benzofuran analog of chloramphenicol as well as its two precursors are reported.

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