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Thiophenes, Pyrazolothiophenes and Pyrimidinothiophenes as Pesticides
Author(s) -
Ram Vishnu Ji
Publication year - 1979
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19793120903
Subject(s) - chemistry , pesticide , pyrazolone , organic chemistry , stereochemistry , medicinal chemistry , agronomy , biology
Several derivatives of 2‐amino‐3‐ethoxycarbonylthiophenes are prepared, of which 3,6 and 8 act as a precursor for syntheses of the pyrazolothiophenes 5,7 and 9 . The structures of these compounds are confirmed by spectral studies and the indirect synthesis of 10c by diazotisation of 1c and coupling with 1‐phenyl‐3‐methyl‐5‐pyrazolone. The condensation of 1 with 3 H ‐methyl‐5‐nitro‐6‐chlorouracil gave 2a, b, c . Reaction of 1c with various acid chlorides and of 1b, c with methyl/phenylisothiocyanate yielded 11c and 12b, c respectively.