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Zur Acetolyse des Piperidinomethyl‐cyclooctanons
Author(s) -
Roth H. J.,
Schumann E.
Publication year - 1969
Publication title -
archiv der pharmazie
Language(s) - German
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/ardp.19693020509
Subject(s) - chemistry , stereochemistry , medicinal chemistry
Die Acetolyse des Piperidinomethyl‐cyclooctanons (I) führt zu etwa 20% Methylencyclooctanon (II), etwa 45% dimerem II (III) und etwa 35% Polymerisat. III lagert Wasser an und geht in 1‐(1‐Hydroxy‐2‐oxo‐cyclooctyl)‐2‐(2‐oxo‐cyclooctyl)‐äthan (IV) über, das kein ketalartiges Isomer bildet.

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