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Negatively correlated cross resistance: Combinations of N ‐methylcarbamate with N ‐propylcarbamate or oxadiazolone for green rice leafhopper
Author(s) -
Yamamoto Izuru,
Kyomura Nobuo,
Takahashi Yoji
Publication year - 1993
Publication title -
archives of insect biochemistry and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.576
H-Index - 66
eISSN - 1520-6327
pISSN - 0739-4462
DOI - 10.1002/arch.940220120
Subject(s) - leafhopper , biology , population , aché , cross resistance , toxicology , acetylcholinesterase , botany , enzyme , biochemistry , genetics , demography , sociology , hemiptera
The use of insecticide mixtures is generally considered to result in the simultaneous development of resistance to the components. However, experiences with leaf and planthoppers do not necessarily support this opinion and indicate that the N ‐methylcarbamate/ N ‐propylcarbamate combination can overcome the resistance of the green rice leafhopper (GRLH) by synergism between the two components. It was found that the N ‐methylcarbamate/oxadiazolone combination gave a similar but more remarkable synergism than the former combination. The mechanism of synergism was studied by the analysis of acetylcholinesterase (AChE) inhibition using the log v‐t plot. AChE from the resistant population is provided with two active sites, one being sensitive to N ‐methylcarbamate and oxadiazolone compounds and the other being insensitive to N ‐methylcarbamates but highly sensitive to oxadiazolones. The overall results indicate that the biochemical mechanism of action of the N ‐methylcarbamat/oxadiazolone combination is essentially the same as that of the N ‐methylcarbamate/ N ‐propylcarbamate combination. Selection of susceptible GRLH by a N ‐methylcarbamate developed the cross‐resistance to the whole N ‐methylcarbamate group; but the population became more susceptible to N ‐propylcarbamates. When further selected by the N ‐methylcarbamate/ N ‐propylcarbamate combination, no further resistance developed to the combination or its components. Thus, certain combinations of insecticides may be useful in resistance management. © 1993 Wiley‐Liss, Inc.