Premium
Identification of four additional myoinhibitory peptides (MIPs) from the ventral nerve cord of Manduca sexta
Author(s) -
Blackburn Michael B.,
Jaffe Howard,
Kochansky Jan,
Raina Ashok K.
Publication year - 2001
Publication title -
archives of insect biochemistry and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.576
H-Index - 66
eISSN - 1520-6327
pISSN - 0739-4462
DOI - 10.1002/arch.1064
Subject(s) - manduca sexta , hindgut , biology , sphingidae , ventral nerve cord , anatomy , manduca , endocrinology , midgut , insect , larva , botany , central nervous system
Four new myoinhibitory peptides were isolated and identified from the ventral nerve cord of adult Manduca sexta . The new peptides are related to two previously identified myoinhibitory peptides also isolated from adult M. sexta , Mas‐MIP I and Mas‐MIP II. The sequences of the new peptides are APEKWAAFHGSWamide (Mas‐MIP III), GWNDMSSAWamide (Mas‐MIP IV), GWQDMSSAWamide (Mas‐MIP V), and AWSALHGAWamide (Mas‐MIP VI). Mas‐MIPs III‐VI were found to inhibit spontaneous peristalsis of the adult M. sexta anterior hindgut (ileum) in vitro. Arch. Insect Biochem. Physiol. 48:121–128, 2001. Published 2001 Wiley‐Liss, Inc.