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WARP: A Unique Extracellular Matrix Component of Cartilage, Muscle, and Endothelial Cell Basement Membranes
Author(s) -
Fitzgerald Jamie
Publication year - 2020
Publication title -
the anatomical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 62
eISSN - 1932-8494
pISSN - 1932-8486
DOI - 10.1002/ar.24087
Subject(s) - extracellular matrix , microbiology and biotechnology , basement membrane , transcriptome , cartilage , function (biology) , matrix (chemical analysis) , biology , extracellular , computational biology , anatomy , chemistry , gene , gene expression , genetics , chromatography
The von Willebrand factor A‐domain‐related protein (WARP) encoded by the VWA1 gene, is an orphan extracellular matrix protein that is expressed in a subset of ECM structures but whose function is poorly understood. Here, recent advances on understanding VWA1/WARP will be reviewed including analysis of VWA1 reporter and global knock‐out mice, interaction studies, and recent transcriptome analyses. Anat Rec, 2019. © 2019 Wiley Periodicals, Inc.