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Stereological Assessment of Developing Mouse Ovarian Follicles in an in vitro Culture System
Author(s) -
Chand Ashwini,
Legge Michael
Publication year - 2011
Publication title -
the anatomical record: advances in integrative anatomy and evolutionary biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 62
eISSN - 1932-8494
pISSN - 1932-8486
DOI - 10.1002/ar.21328
Subject(s) - follicular phase , stereology , andrology , in vitro , ovary , ovarian follicle , ovarian reserve , biology , medicine , endocrinology , pregnancy , infertility , biochemistry , genetics
The aim of this project was to validate the use of ovarian follicular diameter measurement as an indicator of growth using stereology as an independent measure. A strong linear correlation was observed between follicular volume and diameter, and between follicular volume and the total number of granulosa cells. These results have provided a useful validation of a widely used technique for determining follicular growth in vitro. Anat Rec, 2011. © 2011 Wiley‐Liss, Inc.