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Histological Determination of the Areas Enriched in Cholinergic Terminals and m2 and m3 Muscarinic Receptors in the Mouse Central Auditory System
Author(s) -
Hamada Satoko,
Houtani Takeshi,
Trifonov Stefan,
Kase Masahiko,
Maruyama Masato,
Shimizu JunIchi,
Yamashita Toshio,
Tomoda Koichi,
Sugimoto Tetsuo
Publication year - 2010
Publication title -
the anatomical record: advances in integrative anatomy and evolutionary biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 62
eISSN - 1932-8494
pISSN - 1932-8486
DOI - 10.1002/ar.21186
Subject(s) - cholinergic , neuroscience , medial geniculate body , inferior colliculus , nucleus , muscarinic acetylcholine receptor , brainstem , superior colliculus , auditory system , biology , cochlear nucleus , central nervous system , anatomy , receptor , biochemistry
Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor‐expressing cell bodies. Anat Rec 293:1393–1399, 2010. © 2010 Wiley‐Liss, Inc.