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Localization, quantification, and characterization of tuftelin in soft tissues
Author(s) -
Leiser Yoav,
Blumenfeld Anat,
Haze Amir,
Dafni Leah,
Taylor Angela L.,
Rosenfeld Eli,
Fermon Eran,
GruenbaumCohen Yael,
Shay Boaz,
Deutsch Dan
Publication year - 2007
Publication title -
the anatomical record: advances in integrative anatomy and evolutionary biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 62
eISSN - 1932-8494
pISSN - 1932-8486
DOI - 10.1002/ar.20512
Subject(s) - messenger rna , soft tissue , extracellular , microbiology and biotechnology , tissue distribution , hypoxia (environmental) , kidney , biology , protein expression , chemistry , anatomy , pathology , biochemistry , oxygen , endocrinology , medicine , gene , physiology , organic chemistry
Abstract Tuftelin was initially found in the developing and mature extracellular enamel. Here we describe our novel discovery of tuftelin cellular distribution (protein and mRNA) in six soft tissues. The expression levels of tuftelin mRNA were significantly higher in mouse kidney and testis, in which oxygen levels are hovering closely to hypoxia under normal conditions. Anat Rec, 2007. © 2007 Wiley‐Liss, Inc.