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PCL / β‐AgVO 3 nanocomposites obtained by solvent casting as potential antimicrobial biomaterials
Author(s) -
Menezes Beatriz Rossi Canuto,
Montanheiro Thaís Larissa do Amaral,
Sampaio Aline da Graça,
KogaIto Cristiane Yumi,
Thim Gilmar Patrocínio,
Montagna Larissa Stieven
Publication year - 2021
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.50130
Subject(s) - crystallinity , materials science , differential scanning calorimetry , fourier transform infrared spectroscopy , nanocomposite , raman spectroscopy , chemical engineering , polycaprolactone , scanning electron microscope , nuclear chemistry , chemistry , nanotechnology , composite material , polymer , physics , optics , engineering , thermodynamics
The adhesion of microorganisms on biomaterials can impair its effective application. The addition of antimicrobial agents is a promising alternative to overcome this limitation. In this work, films of polycaprolactone (PCL) and nanostructured β‐AgVO 3 (SV) were produced by solvent casting with 0.1, 0.5, and 1.0 wt% of SV. The effect of SV on the structure of PCL was investigate using Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), Raman spectroscopy, differential scanning calorimetry (DSC), and scanning electron microscopy (SEM). The antimicrobial activity of the films against Staphylococcus aureus and Escherichia coli was evaluated by the agar diffusion method and by direct contact test. FTIR confirmed the presence of SV into the PCL films, with chemical interaction between them. SEM showed that SV nanorods were well dispersed and with good interfacial adhesion with PCL. XRD diffraction and Raman spectroscopy showed that the presence of SV increased the number of nucleation sites, reducing the size of crystallites and increasing the amorphous domains in the PCL matrix, consequently reducing crystallinity. This behavior was confirmed by DSC, which showed a reduction in the crystallinity with increasing SV content. Films with 1 wt% of SV showed antimicrobial activity against Staphylococcus aureus in direct contact test.