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Cover Image, Volume 137, Issue 43
Author(s) -
Modak Piyush,
Hammond Willis,
Jaffe Michael,
Nadig Malavika,
Russo Richard
Publication year - 2020
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.49828
Subject(s) - schiff base , shrinkage , materials science , volume (thermodynamics) , cover (algebra) , polymer chemistry , base (topology) , porosity , computer science , chemical engineering , nanotechnology , composite material , physics , engineering , thermodynamics , mechanical engineering , mathematical analysis , mathematics
This figure by Piyush Modak and colleagues shows a patented porous architecture (20 x magnification) formed by a dynamic Schiff base network between acrylated chitosan (aCHN) & oxidized dextran (oDEX). This aCHN‐oDEX network is a tunable, platform technology with various medical applications. Schiff base bonds in this network are mobile and reversible allowing additional Schiff base bonds to form over time, leading to a lower energy state and densification. In addition, the network shrinks, even when completely immersed in physiological solution, instead of swelling. And the shrinkage allows the 3D network to be used in enclosed structures such as the brain and spine. DOI: 10.1002/app.49756