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Electrospun mat of thermal‐treatment‐induced nanocomposite hydrogel of polyvinyl alcohol and cerium oxide for biomedical applications
Author(s) -
More Namdev,
Ranglani Deepak,
Kharche Shubham,
Kapusetti Govinda
Publication year - 2020
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.49426
Subject(s) - vinyl alcohol , materials science , self healing hydrogels , polyvinyl alcohol , biocompatibility , crystallinity , fourier transform infrared spectroscopy , nanocomposite , composite material , chemical engineering , swelling , polymer chemistry , polymer , engineering , metallurgy
Hydrogels are one of the most thought‐provoking formulations used widely for biomedical applications. In the present investigation, poly(vinyl) alcohol (PVA) and its cerium oxide (CO) composite‐based hydrogels were prepared by the combination of electrospinning and thermal processing technique. The partial crosslinking, along with time‐controlled heating (10 min), delivered PVA hydrogel. The mechanism was explained with Fourier‐transform infrared spectroscopy analysis, where the hydroxyl group disappeared in long‐duration (30 min) of heat treatment and they retain in lesser duration. The heat‐treated PVA transformed from amorphous to crystalline, since the T g of PVA disappeared in 30 min heat treatment, while the T g increased to 85°C (10 min heat treatment) from 70°C in PVA, suggested the full and partial crystallinity. The swelling and porosity studies reveal the hydrogel formation of heat‐treated PVA. Interestingly, CO reinforced PVA composites show better swelling with respect to heat‐treated PVA. Furthermore, CO reinforced PVA hydrogel demonstrated better biocompatibility platelet adhesion and accelerated wound healing competence.