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Rheology, injectability, and bioactivity of bioactive glass containing chitosan/gelatin, nano pastes
Author(s) -
Sohrabi Mehri,
Eftekhari Yekta Bijan,
Rezaie Hamid R.,
NaimiJamal Mohammad R.
Publication year - 2020
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.49240
Subject(s) - gelatin , chitosan , materials science , rheology , scanning electron microscope , simulated body fluid , fourier transform infrared spectroscopy , bioactive glass , chemical engineering , aqueous solution , composite number , dynamic mechanical analysis , composite material , nuclear chemistry , chemistry , organic chemistry , polymer , engineering
Bioactive pastes containing bioactive sol–gel derived glass (BG) and various amounts of chitosan (Cn) and gelatin (Gel) were prepared in this study. To be exact, three pastes were prepared by mixing 25 parts by weight of glass powder with (a) 100 parts by weight of a 3 wt% acetic acid‐based chitosan solution, (b) 100 parts by weight of a 3 wt% water‐based gelatin solution, and (c) 100 parts by weight of a solution containing equal amounts of the above‐mentioned solutions. The bioactivity of the composite samples was evaluated by the immersion of the prepared pastes into the simulated body fluid (SBF) solution. The samples were also analyzed by X‐ray diffractometry (XRD), Brunauer–Emmett–Teller (BET), scanning electron microscope (SEM), Fourier transform infrared (FTIR), and atomic absorption spectroscopy (AAS). The results indicated better apatite formation capacity on the glass‐/chitosan‐/gelatin‐injected paste after 14 days. Furthermore, unlike the chitosan containing paste, the gelatin‐containing sample was injectable and displayed viscoelastic behavior as determined by conducting the rheology test in oscillation mode. In addition, while chitosan made the paste more viscous, it improved the washout resistance when compared to the gelatin‐containing sample. The experimental results also indicate the formation of spherical calcites in the pastes prior to immersion into the SBF solution.