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Cover Image, Volume 137, Issue 16
Publication year - 2020
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.49024
Subject(s) - fibroin , cover (algebra) , globular cluster , polymer science , computer science , nanotechnology , physics , chemistry , materials science , engineering , astrophysics , composite material , silk , mechanical engineering , stars
The cover image created by Mariana Agostini de Moraes and colleagues, represents the self‐assembling of silk fibroin into globular structures within a continuous fibroin membrane matrix, encapsulating the drug model ‐ diclofenac sodium. These structures were only observed when the drug was incorporated in the fibroinsolution, prior to membrane preparation. The formation was spontaneous, and the globular structures presented regular size, shape and uniform distribution within the membrane. EDX mapping (red dots) of a fractured particle confirmed the high concentration of the drug within the globular structures. These results emphasize the potential use of silk fibroin for drug delivery applications. DOI: 10.1002/app.48763