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Swelling and rheological study of calcium phosphate filled bacterial cellulose‐based hydrogel scaffold
Author(s) -
Basu Probal,
Saha Nabanita,
Saha Petr
Publication year - 2020
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.48522
Subject(s) - swelling , materials science , swelling capacity , polyvinylpyrrolidone , chemical engineering , calcium , rheology , ethylene glycol , self healing hydrogels , phosphate , chemistry , composite material , polymer chemistry , organic chemistry , engineering , metallurgy
This work focuses mainly about swelling and rheological properties of calcium phosphate filled bacterial cellulose (BC)‐based hydrogel scaffolds. Calcium phosphate is incorporated in the form of hydroxyapatite (HA) and β‐tricalcium phosphate (β‐TCP) in different ratios, that is, 00:00, 10:90, 20:80, 40:60, 50:50, and 60:40. These scaffolds are also comprised with polyvinylpyrrolidone (PVP), poly(ethylene glycol), agar, and glycerin; designated as “BC‐PVP” and “BC‐PVP‐β‐TCP/HA.” All the hydrogel scaffolds are showing the notable viscoelastic property at 28 and 37 °C temperatures. The degree of swelling is found significant in BC‐PVP‐β‐TCP/HA_50:50 scaffold and it is notably elastic at 37 °C after 5 min of swelling. However, after 60 min of swelling and at equilibrium swelling state, the elastic property of BC‐PVP‐β‐TCP/HA_20:80 is revealed the highest. Considering the degree of swelling and rheological properties, the BC‐PVP‐β‐TCP/HA_50:50 and BC‐PVP‐β‐TCP/HA_20:80 hydrogel scaffolds found suitable for their application in bone tissue engineering or bone tissue regeneration. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137 , 48522.