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Hydrogel films and microcapsules based on soy protein isolate combined with alginate
Author(s) -
Tansaz Samira,
Durmann AnnKatrin,
Detsch Rainer,
Boccaccini Aldo R.
Publication year - 2017
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.44358
Subject(s) - self healing hydrogels , soy protein , biocompatible material , biodegradation , materials science , immunogenicity , regeneration (biology) , fibroblast , cell encapsulation , tissue engineering , chemical engineering , chemistry , polymer chemistry , biomedical engineering , microbiology and biotechnology , biochemistry , in vitro , biology , organic chemistry , medicine , immune system , engineering , immunology
ABSTRACT Alginate hydrogels are combined with soy protein isolate (SPI), a plant derived protein with low immunogenicity, appropriate biodegradability and low cost, to produce biocompatible films, and microcapsules. The cell–material interaction is assessed through the use of mouse embryotic fibroblast cells (MEF cells) on films, and the results illustrate that the alginate/SPI hydrogel films support cell attachment, spreading, and proliferation. Cell biology results combined with degradation studies suggest that such hydrogels are promising biomaterials for soft tissue regeneration or as wound dressing materials. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44358.