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Effect of crosslinking procedure on structural, thermal, and functional performances of cellulosic nanofibers: A comparison between chemical and photochemical crosslinking
Author(s) -
Khorshidi Sajedeh,
Solouk Atefeh,
Karkhaneh Akbar,
Mirzadeh Hamid,
Sharifi Shahriar,
Mazinani Saeedeh
Publication year - 2016
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.43832
Subject(s) - nanofiber , electrospinning , materials science , cellulose , thermal stability , chemical engineering , aqueous solution , polymer chemistry , nanocellulose , porosimetry , tissue engineering , composite material , polymer , porosity , chemistry , porous medium , organic chemistry , biomedical engineering , engineering , medicine
In the current study, hydroxyethyl cellulose (HEC) based nanofibers were fabricated through electrospinning and then made water insoluble by chemical and photochemical crosslinking. Structural, thermal, and functional performances of electrospun fibers before and after crosslinking were fully assessed by a numerous techniques including microscopy, porosimetry, mechanical analysis, and cell culture study. Both crosslinking procures were found to able to preserve fibrous structure in an aqueous environment for short times, however; chemical process conferred better long‐term morphological stability and cell compatibility. These findings suggest that chemically crosslinked HEC mats may perform as a promising electrospun tissue engineering scaffold. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43832.