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BSA imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres
Author(s) -
Liu Jiangquan,
Ying Xiaoguang,
Wang Hongxun,
Li Xiao,
Zhang Weiying
Publication year - 2016
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.43617
Subject(s) - microsphere , polyethylene glycol , calcium alginate , calcium , materials science , self healing hydrogels , chemical engineering , peg ratio , polymer chemistry , copolymer , polyethylene , polymer , composite material , finance , economics , engineering , metallurgy
Polyethylene glycol grafted calcium alginate hydrogel microspheres are synthesized by ring‐opening and addition reaction of epoxy chloropropane. FTIR, 13 C NMR, optical microscope, SEM, TG, and DSC are used for characterization. Swelling behaviors are studied and it is found that polyethylene glycol grafted calcium alginate microspheres are improved in anti‐swelling properties. Protein‐imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres exhibit enhanced specific rebinding quantity (11.16 mg/g) and selective recognition properties (4.71 against BHb), towards target molecule in the presence of competing protein, compared with that of the unmodified samples (4.96 mg/g and 1.75, respectively). © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43617.