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Inside Cover, Volume 133, Issue 14
Publication year - 2016
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.43406
Subject(s) - decellularization , pericardium , cover (algebra) , polymer science , world wide web , chemistry , computer science , biomedical engineering , medicine , tissue engineering , engineering , surgery , mechanical engineering
Sasan Jalili‐Firoozinezhad, Sareh Rajabi‐Zeleti, Anna Marsano, Nasser Aghdami and Hossein Baharvand discuss the preparation of decellularized pericardium membranes by a mild devitalization process on human pericardium tissue, where most of the native extracellular cues are preserved, while more than 99% of cellular components are removed. Decellularized pericardium, as a bioactive material, not only supports survival, metabolism and proliferation of cardiac stem cells, but also promotes their differentiation into mature cardiomyocytes. This native biomaterial could find use in various cardiovascular applications, such as valve replacement, cardiac patches and vascular grafts. (DOI: 10.1002/app.43255 )