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Cover Image, Volume 133, Issue 12
Publication year - 2016
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.43264
Subject(s) - prodigiosin , chromobacterium violaceum , quorum sensing , serratia marcescens , chemistry , biofilm , ezrin , microbiology and biotechnology , physics , computer science , nanotechnology , bacteria , biology , materials science , escherichia coli , gene , biochemistry , cell , cytoskeleton , genetics
Quorum sensing (QS) is the bacterial cell‐to‐cell communication system regulated by the concentration of n‐acylhomoserine lactone (AHL) as the main signaling molecule in gram‐negative bacteria. QS is inhibited by β–cyclodextrin (β–CD)‐modified core‐shell microspheres. On page 43198 (1 of 7), Chigusa Okano, Eri Nasuno, Ken‐ichi Iimura and Norihiro Kato confirm the effective trapping of the AHL on CDs using a bioassay with the AHL‐negative mutant Chromobacterium violaceum CV026. The impact of the quenching effect is successfully demonstrated by a change in color tone of the Serratia marcescens AS‐1 culture, because the production of the red pigment prodigiosin is enabled to reduce by inhibitory expression of a QS‐dependent gene, pig cluster , in the AS‐1 strain. (DOI: 10.1002/app.43198 )