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Cover Image, Volume 133, Issue 6
Publication year - 2016
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.43093
Subject(s) - polymer science , cationic polymerization , acrylate , copolymer , citation , polymer , polyelectrolyte , biopolymer , computer science , materials science , chemistry , polymer chemistry , chemical engineering , composite material , world wide web , engineering
On page 1480, Annalisa Dalmoro, Alexander Y. Sitenkov, Gaetano Lamberti, Anna Angela Barba, and Rouslan I. Moustafine discuss an enteric shell‐core microparticle encapsulating indomethacin produced by a solvent‐free method based on ultrasonic atomization and a two‐stage polyelectrolyte complexation. In particular, a water solution of the anionic biopolymer alginate containing indomethacin was sprayed first in fine droplets complexed with the cationic (meth)acrylate copolymer Eudragit ® E 100, and then with the anionic copolymer Eudragit ® L30D‐55. The first complexation stage was applied to achieve a high drug encapsulation efficiency; the second one to assure gastroresistance. (DOI: 10.1002/app.42976 )