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Acrylic bone cements: Effects of the poly(methyl methacrylate) powder size and chitosan addition on their properties
Author(s) -
Endogan Tugba,
Kiziltay Aysel,
Kose Gamze Torun,
Comunoglu Nil,
Beyzadeoglu Tahsin,
Hasirci Nesrin
Publication year - 2014
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.39662
Subject(s) - materials science , methyl methacrylate , biocompatibility , composite material , curing (chemistry) , particle size , chitosan , compressive strength , poly(methyl methacrylate) , methacrylate , acrylic resin , bone cement , cement , polymer chemistry , chemical engineering , polymer , copolymer , engineering , coating , metallurgy
The effect of the particle size of poly(methyl methacrylate) (PMMA) and the incorporation of chitosan (CH) on the mechanical and thermal properties and the biocompatibility of acrylic bone cements were investigated. Three groups of bone cements were prepared with different PMMA particles. Groups 1 (BC1) and 2 (BC2) contained ground and sieved PMMA with particle sizes in the ranges 50–150 μm and 1–50 μm, and group 3 (BC3) contained synthesized PMMA microspheres with a size of about 1 μm. The mechanical properties of the three groups were similar, but their curing properties were significantly affected. The presence of CH improved the mechanical and thermal properties. For the BC1 group, the compressive strength increased more than 10 MPa, and the curing temperature decreased 12°. The cement having the optimum properties (BC1) was applied to rats, where it enhanced the bone bonding ability, and bioactivity was observed. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131 , 39662.