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Studies on inherently radiopaque acrylate copolymers for biomedical applications
Author(s) -
Dawlee S.,
Jayabalan M.
Publication year - 2012
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.36457
Subject(s) - glycidyl methacrylate , copolymer , methacrylate , radiodensity , materials science , polymer chemistry , monomer , acrylate , glass transition , polymer , composite material , medicine , radiography , radiology
Poly(glycidyl methacrylate‐ co ‐ethyl methacrylate) and poly(glycidyl methacrylate‐ co ‐butyl methacrylate) random copolymers (with 50–50 mol % of monomers) were made radiopaque by grafting iodine moieties through the ring opening reaction of the epoxy groups. The percentage weight of grafted iodine in the copolymers was found to be as high as 19%. The iodinated copolymers showed higher glass transition temperature and thermal stability in comparison with the parent copolymers. Iodinated copolymer of poly(glycidyl methacrylate‐ co ‐ethyl methacrylate) has improved glass transistion temperature than iodinated poly(glycidyl methacrylate‐ co ‐butyl methacrylate). Radiographic analysis of these iodinated copolymers showed excellent radiopacity. The in vitro cytotoxicity tests revealed cytocompatibility with cells. These radiopaque copolymers are expected to find application as dental and orthopedic cements. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012