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Fabrication and properties of degradable poly(amino acid)/nano hydroxyapatite bioactive composite
Author(s) -
Zhao Zhitong,
Shan Wenpeng,
Zhang Yunfei,
Li Xiangde,
Ma Jian,
Yan Yonggang
Publication year - 2012
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.36355
Subject(s) - differential scanning calorimetry , diffractometer , composite number , crystallinity , materials science , scanning electron microscope , dynamic mechanical analysis , glass transition , x ray photoelectron spectroscopy , fourier transform infrared spectroscopy , crystallization , chitosan , chemical engineering , bioactive glass , nuclear chemistry , composite material , polymer chemistry , polymer , chemistry , physics , engineering , thermodynamics
Poly(amino acid)/nano hydroxyapatite (PAA/n‐HA) bioactive composite was prepared by in situ melting polymerization. The composition, structure and morphology as well as glass transition temperature ( T g ), dynamic mechanical properties of the PAA/n‐HA composite were characterized by infrared spectrometer, X‐ray diffractometer, X‐ray photoelectron spectroscopy, scanning electron microscope, differential scanning calorimeter, and dynamic mechanical analyzer. The results indicated that the n‐HA particles were uniformly distributed into PAA matrix and some interactions were found at the interface between PAA and n‐HA, and the crystallinity of PAA in the composite decreased with the increase of n‐HA content. The T g and storage modulus of the composite increased with increasing n‐HA content, demonstrating that the n‐HA content had obvious effects on the crystallization kinetic parameters and thermo properties of the PAA/n‐HA composite. In addition, the n‐HA amount had evident effects on the degradation of the PAA/n‐HA composite in phosphate buffered saline (PBS), and the weight loss ratio of the composite decreased with the increase with n‐HA content. The pH value of the medium was stable around 7.40 after the composite immersion into PBS for 8 weeks. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012