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Polyurethane‐based biomaterials for shape‐adjustable cardiovascular devices
Author(s) -
Silvestri A.,
Serafini P. M.,
Sartori S.,
Ferrando P.,
Boccafoschi F.,
Milione S.,
Conzatti L.,
Ciardelli G.
Publication year - 2011
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/app.34779
Subject(s) - polyurethane , materials science , hydrolysis , extender , composite number , composite material , polymer chemistry , chemical engineering , polymer science , chemistry , organic chemistry , engineering
A series of biostable polyurethane (PUR) formulations, including a composite containing a clay as filler, were prepared as new biomaterials for cardiovascular applications. Poly(dimethyl siloxane) and poly(tetramethylene oxide) were selected as macrodiols because of their mechanical properties and the high hydrolysis resistance they confer to PURs. 1,6‐Diisocyanatohexane and 1,4‐cyclohexane dimethanol were used as a diisocyanate and chain extender, respectively. The polymeric products were chemically, thermally, and mechanically characterized. Thermomechanical characterizations highlighted that some of the obtained formulations are promising materials for applications in the cardiovascular field, in particular, for the realization of annuloplastic rings in mitral valve repair. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011